Search on: RECEPTOR, EPIDERMAL GROWTH FACTOR 
Descriptors Found: 1
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Descriptor English:   Receptor, Epidermal Growth Factor 
Descriptor Spanish:   Receptor del Factor de Crecimiento Epidérmico 
Descriptor Portuguese:   Receptor do Fator de Crescimento Epidérmico 
Synonyms English:   c-erbB-1 Protein
EGF Receptor
Epidermal Growth Factor Receptor
Receptors, Epidermal Growth Factor-Urogastrone
Receptor, Transforming-Growth Factor alpha
Urogastrone Receptor
Receptor, TGF-alpha
Receptor, Urogastrone
Transforming Growth Factor alpha Receptor
TGF-alpha Receptor
erbB-1 Proto-Oncogene Protein
Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
Receptor, EGF  
Tree Number:   D08.811.913.696.620.682.725.400.100
D12.776.543.750.060.249
D12.776.543.750.750.360.300
D12.776.543.750.750.400.340
Definition English:   A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. 
Indexing Annotation English:   DF: RECEPT EGF
History Note English:   2000(1987); for EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, EPIDERMAL GROWTH FACTOR 1994-1999 
Allowable Qualifiers English:  
administration & dosage agonists
antagonists & inhibitors analysis
biosynthesis blood
chemistry classification
drug effects deficiency
genetics history
immunology isolation & purification
metabolism physiology
radiation effects therapeutic use
ultrastructure  
Record Number:   24479 
Unique Identifier:   D011958 

Occurrence in VHL:
 

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